7 Best Night Serums for Sensitive Skin To Buy In 2023

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Sensitive skin requires a delicate balance of potent ingredients and gentle care, particularly when it comes to nightly skincare routines. Night serums, packed with active ingredients, can work wonders on your skin while you sleep, provided you choose the right formula. For those with sensitive skin, it’s important to find serums that deliver results without causing irritation.

Here are the 7 best night serums that promise to nurture and rejuvenate sensitive skin.

7 Best Night Serums for Sensitive Skin

1. Cetaphil Redness Relieving Night Moisturizer

Cetaphil is renowned for its gentle skincare products, and their Redness Relieving Night Moisturizer is no exception. It is specifically designed for sensitive skin, offering hydration and soothing redness without causing irritation.

Key Ingredients:

  • Hyaluronic acid for hydration
  • Licorice extract and allantoin for soothing
Fragrance-freeMay not be as potent for anti-aging concerns
Clinically proven to reduce redness

2. La Roche-Posay Toleriane Ultra Overnight

La Roche-Posay’s Toleriane range is tailor-made for sensitive skin. The Ultra Overnight serum is no exception, working to calm the skin and reduce discomfort overnight.

Key Ingredients:

  • Neurosensine to soothe irritation
  • Thermal spring water for hydration
Free from preservativesHigher price point
Intense hydration
Non-greasy formula

3. Burt’s Bees Nightly Hydration Serum

For those who prefer natural skincare options, Burt’s Bees Nightly Hydration Serum is an excellent choice. It uses natural ingredients to gently moisturize and replenish the skin.

Key Ingredients:

  • Royal Jelly to enhance skin’s texture
  • Aloe water to soothe
99% natural ingredientsMay require patch testing due to natural extracts
No parabens, phthalates, petrolatum or SLS

4. Aveeno Calm + Restore Triple Oat Serum

Aveeno’s expertise in skin-soothing ingredients shines through in their Calm + Restore Triple Oat Serum. This serum is specially formulated for sensitive skin, providing nourishment and reducing redness.

Key Ingredients:

  • Oat extract to soothe the skin
  • Feverfew extract to calm
Oat complex for sensitive skinMay not be suitable for very oily skin types
Lightweight texture

5. Neutrogena Hydro Boost Hydrating Serum

Neutrogena’s Hydro Boost Hydrating Serum is an excellent choice for sensitive skin that needs a hydration boost. Its gel-like consistency feels light on the skin and is highly effective.

Key Ingredients:

  • Hyaluronic acid for moisture
  • Glycerin for hydration
Non-comedogenicContains fragrance, which may irritate some users
Oil-free formula

6. Eucerin Q10 Anti-Wrinkle Face Serum

Eucerin’s Q10 Anti-Wrinkle Face Serum combines the need for anti-aging care with the necessity of being gentle on sensitive skin.

Key Ingredients:

  • Coenzyme Q10 to energize skin cells
  • Antioxidants to protect skin
Formulated for sensitive skinTexture might be too rich for some
Fragrance-free and alcohol-free

7. First Aid Beauty Ultra Repair Hydrating Serum

First Aid Beauty’s Ultra Repair Hydrating Serum lives up to its name by deeply moisturizing the skin without causing irritation, thanks to its skin-friendly ingredients.

Key Ingredients:

  • Hyaluronic acid for hydration
  • Collodial oatmeal to soothe
Safe for sensitive skinSlightly more expensive
Free from harsh chemicals and colorants

Important Note:
“Always conduct a patch test when trying a new serum, particularly if you have sensitive skin. This will help you avoid potential allergic reactions or irritation.”

Frequently Asked Questions About Night Serum for Sensitive Skin

What is a night serum for sensitive skin?

A night serum for sensitive skin is a skincare product designed with gentle ingredients to target specific skin concerns like hydration, fine lines, or dullness without causing irritation or redness often experienced by sensitive skin types.

How does a night serum differ from a night cream?

A night serum typically has a higher concentration of active ingredients and a lighter texture than a night cream. Serums are formulated to penetrate deeply into the skin, while creams provide a protective barrier to lock in moisture.

Can I use night serum if I have acne-prone sensitive skin?

Yes, you can use a night serum if you have acne-prone sensitive skin, but choose a non-comedogenic formula that is free from oils and irritants known to exacerbate acne.

How often should I apply night serum?

Most night serums are designed for daily use as part of your nighttime skincare routine, but it’s important to follow the specific instructions on the product you choose.

Do I need to use a moisturizer after applying a night serum?

Yes, it is often recommended to apply a moisturizer after your serum to help seal in the serum’s active ingredients and to provide additional hydration.

What ingredients should I look for in a night serum for sensitive skin?

Look for soothing ingredients like hyaluronic acid, niacinamide, ceramides, and natural extracts known for their calming properties, such as aloe and oatmeal.

What ingredients should I avoid in a night serum if I have sensitive skin?

Avoid potentially irritating ingredients like alcohol, synthetic fragrances, and strong retinoids or acids. Always check the label for ingredients that you know your skin reacts to.

How do I test if a night serum is suitable for my sensitive skin?

Perform a patch test by applying a small amount of serum to a discreet area of skin, like behind your ear or on the inside of your elbow, and wait 24-48 hours to see if there is a reaction before applying it to your face.

Will a night serum cure my skin sensitivity?

While a night serum can significantly soothe and improve the condition of sensitive skin, it is not a cure. Skin sensitivity can be managed with the right skincare routine and by avoiding known triggers.

Can I use night serum around my eyes?

The skin around the eyes is particularly delicate. Unless the serum is specifically labeled as safe for the eye area, it is best to use a separate eye cream formulated for that region.

How long does it take to see results from a night serum?

Results can vary based on the serum’s active ingredients and your skin type. Some people may see immediate hydration, while other benefits, like reduced fine lines or improved texture, can take several weeks of consistent use.

Can a night serum expire?

Yes, like all skincare products, night serums have an expiration date. The potency of the active ingredients can diminish over time, especially after the product is opened. Check the packaging for the shelf life and pay attention to any changes in color, texture, or smell.


Choosing a night serum for sensitive skin doesn’t have to be a daunting task. The key is to look for products that have a good balance of hydration, soothing properties, and are free from common irritants.

The serums listed above are some of the best options in the market that cater to the delicate nature of sensitive skin, each with its unique blend of ingredients

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